Thursday, May 19, 2016

Is oxygen beneficial in patients with myocardial infarction?

In classic teaching in medical school, we were told to give supplemental oxygen to patients with myocardial infarction. But in the era of evidence based medicine this may be not true for everyone. The AVOID trial has addressed tis issue. The AVOID investigators has found that oxygen in the non-hypoxic STEMI patients was associated with increased infarction size (detected by CMR), increased rate of re-infarction and increased incidence of ventricular arrhythmias. So, it is not recommended to give supplemental oxygen if the patient is not hypoxic on room-air, i.e. the patient has SO2 above 94%. This may be explained by the increased formation of oxygen free radicles that are associated with more myocardial injury (chemical rather than ischemic).

This is a link to the AVOID study results.

1 comment:

  1. Thanks for writing this in depth post. You covered every angle. It’s not just a skeleton but these things "got meat on her bones."You can also check our healthcare marketing site Techno Data Group to build a sales funnel to build trust, develop relationship and prove your expertise with verified healthcare professionals contact database.Cardiologist Email List

    ReplyDelete